Name:   ANDREI VALENTIN MEDVEDOVICI  Date of birth:  November 29th, 1961 Place of birth:  Bucharest Address:  Bucharest-061945, Aleea Parva #6, C37, Apt.201 Phone:  +40 723 330 423 E-mail:  avmedved@yahoo.com Nationality:  Romanian  Civil status:  married Education: Date Earned Degree(s) or Diploma(s)/Institution 1980 Bachelor, Industrial College no. 33, Bucharest. 1984 B.Sc., Polytechnic Institute of Bucharest, Faculty of Chemistry. 1985 M.Sc. in Analytical Chemistry, Polytechnic Institute of Bucharest, Faculty of Chemistry. 1994 Ph.D., University of Bucharest, Faculty of Chemistry (thesis entitled “Metal Complexes in Chromatographic Techniques”, coordinator Prof. G.E. Baiulescu, Ph.D.) Professional experience:  Period Location Position Description Institution/Company 1985 - 1998 Romania, Fagaraş Chemist Optimisation of technological process, chemistry of Research Centre for Technology explosives 1998 -1990 Romania, Bucharest Researcher Laboratory for microbiological growth substrates Research Institute   Dr. I. Cantacuzino 1990 - 1998 Romania,Bucharest Teaching Assistant Qualitative Analytical Chemistry, Separation Sciences, Trace Analysis (courses held in 1998 - 2000 University of Bucharest, Lecturer   French and English) 2000 - 2005 Faculty of Chemistry Associate Professor   since 2005 Professor   since 2006 Ph.D. Coordinator 1997 - 2000 Romania, Bucharest QA consultant Implementation of GMP/GLP SINDAN 1997 - 2002 Romania, Bucharest QA consultant Quality control, analytical methods validation, equipments qualification , process 2002 - 2009 Labormed Pharma R&D manager validation, bioequivalence since 2009 Romania, Bucharest Scientific Director  Bioanalysis Labormed Group Study grants: Period Institution Position Description 1991 - 1992 University of Ghent (RUG) Ph.D. student Separation sciences, metal complexes and applications in chromatographic techniques Gent, Belgium 1994 - 1996 University of Ghent (RUG) Post Doc. HPLC, SFC, GC/MS applications in environmental, food, chiral separation field; Gent, Belgium Hyphenated techniques Language skills: (1-Excellent; 5-Basic) Language    Reading     Speaking     Writing French 1 1 2 English 2 3 2 Membership of professional bodies:   Romanian Analytical Chemical Society.  Awards:   C.D. Nenitescu Award of the Romanian Academy, December 2009.  Editorial board member:  Journal of Liquid Chromatography & Related Technologies (Taylor & Francis Group, U.S.A.) – ISSN 1082-6076;   Bioanalysis (Future Science Ltd., U.K.) – ISSN 1757-6199;  Journal of Environmental Chemistry and Ecotoxicology (Academic Journals) – ISSN 2141-226X.  Advisory board member for journals: Journal of Chromatography A; Journal of Chromatography B;  Journal of Pharmaceutical and Biomedical Analysis; Analytical Bioanalytical Chemistry, Chromatographia; Analytical Letters; European Journal of Pharmaceutics and Biopharmaceutics, International Journal of Environmental Analytical Chemistry, Journal of Medicinal Plant Research, Scientia Pharmaceutica, Journal of Separation Science, Revue Roumaine de Chimie; Revista de Chimie, Studia Universitatis Chemia UBB. Evaluation board member: CNCSIS; RENAR; ARACIS  Other relevant information: invited scientist  #     Period      Institution Domain 1 Aug.-Oct. 1997 Research Institute for Chromatography,   On-line SPE /HPLC or SFC  2 Aug.-Oct. 1998 Kortrijk, Belgium  SFC/SFC/UV 3 Aug.-Oct. 1999 SFE/GC/MS 4 Aug.-Oct. 2000 SFC/MS of polysaccharides 5 Aug.-Oct. 2001 SFC/MS in pharma applications Competence profile: Separation sciences; Sample preparation (LLE, SPE, SPME, SFE); Chromatographic techniques (HPLC, PC-SFC, CGC); Detection in chromatographic techniques (DAD, FLD, RID, ELSD; MS and MS/MS); Automation in chromatography (on-line SPE/HPLC); Multidimensional/comprehensive chromatography (LC/LC; LC/GC; SFC/LC); Hyphenation in separation techniques (LC/MS-MS, SFC/MS-MS, CGC/MS); Development and validation of separation methods; Qualification of the analytical instrumentation; Application fields: bioanalysis, pharmaceuticals, environmental, food chemistry. Participation to projects: 1.    Team manager/Chemistry Section, EPTISA Projectos Internationales S.A., for EU Phare (Europe Aid/115101/D/SV/RO/1 – Strengthening of the institutional and administrative capacity of MoH to adopt and implement the acquis communautaire in the field of water and health related risks”, 2004-2005). 2.  Training responsible, subcontract no. 540789, Project Phare RO, 2004/IB/Ag-01, Ministry of Agriculture, 2004. 3.  Team member, Leonardo Da Vinci Project (“Training Module for Environmental monitoring and pollution control”, RO-02BFPP-141004, coordinator Prof. Dr. A. Danet, University of Bucharest, 2004). 4.  Team member, CEEX project 107/09.10.2006 (“Nanostructurate azopolymers and their application in microelectronics and biology”, coordinator Prof. Dr. N. Hurduc, Technical University Gh. Asachi, Iasi). 5.  Project manager, contract 927/02.12.2004 between Labormed Pharma and the University of Bucharest. Trainer: (training sessions having duration between 3 and 5 days, as a single trainer)  # Beneficiary Training Title Date 1 Coca-Cola Romania s.r.l. New trends in GC Ian. 2004 2 Coca-Cola Romania s.r.l Gas Chromatography – system qualification and method validation Oct. 2006 3 Regia Apele Romane Chromatographic methods in water control Dec. 2007 4 Inspectorate for Public Veterinary Health Bucharest Basic aspects in chromatographic techniques. Applications in May 2005 (ISPVB) food quality control 5 Zentiva (Sanofi Aventis) Romania Chromatographic Methods Nov. 2010 Publications: ISI indexed: Journal Titles (no. of published works + accepted manuscripts) Acta Endocrinologica (1); Advances in Chromatography (1); Analytical Letters (7); Analytical Methods (1); Annali di Chimica (2); Arzneimittel-Forschung-Drug  Research (1); Bioanalysis (1+1); Biomedical Chromatography (7+1); Chemia Analityczna (4); Chirality (1); Chromatographia (1); Chemistry-A European Journal  (1); Comptes Rendus Chimie (1); Farmacia (1); European Journal of Drug Metabolism and Pharmacokinetics (1); Journal of Applied Toxicology (1); Journal of  Catalysis (1); Journal of Chemical Information and Computer Sciences (1); Journal of Chemometrics (1); Journal of Chromatography A (5); Journal of  Chromatography B (4); Journal of High Resolution Chromatography & Chromatography Communications (4); Journal of Inclusion Phenomena and Inclusion  Chemistry (1); Journal of Liquid Chromatography & Related Technologies (9); Journal of Microcolumn Separations (2); Journal of Pharmaceutical and  Biomedical Analysis (7); Journal of Separation Science (3); LC-GC Europe (1); Microcehemical Journal (4); Nukleonika (1); Revue Roumaine de Chimie (13);  Separation Science and Technology (1); Talanta (1); Water Research (1+1) Total:  95 publications (80 in international journals);  Cumulated impact factors of journals:   161.9 Cumulated relative influence score of journals:   77.82.  Non-ISI: Analele Universitatii Bucuresti (2); Archives of the Medical Balkan Union (1); European Pharmaceutical Review (1); International Environmental Technology (2);  LC-GC International (1); Proceedings of the International Symposium of Capillary Chromatography (5); Southern Brazilian Journal of Chemistry (1);  Total:  13  (10 in international journals).  Chapters in books/encyclopedias, published courses  5 published courses (University of Bucharest Publishing House);  4 chapters in books (international publishers);  6 chapters in books (national publisher);  10 chapters in international encyclopedias – Encyclopedia of Chromatography (4);  Encyclopedia of Separation Science (1);  Encyclopedia of Analytical Science (4);  Encyclopedia of Endocrinology and Endocrine Diseases (1).  The complete list of works may be found on  www.unibuc.ro/prof/medvedovici_a_v in CV of Andrei Valentin  Medvedovici and on www.researcherid.com/rid/C2543-2011 h-Index: 13 Citations: 589 (485 without self citations). Scientific contributions from the period 2001-2011  ISI publications:  71 Chapters in International Encyclopedias:  8  Distribution of publications per years:  2001 – 3; 2002 – 5; 2003 – 4; 2004 – 5; 2005 – 8; 2006 – 2; 2007 – 10; 2008 – 4; 2009 – 8; 2010 – 15; 2011 -  7. Cumulated Impact Factor of journals:  112.233 Cumulated Relative Influence Score of journals:   59.095 Citations of the publications (with-out self-citations):  243 Number of publications per journal (journals in descending order of their Impact Factors):  Journal of Catalysis (1); Water Research (2); Journal of Chromatography A (2); Journal of Chromatography B (4); Advances in Chromatography (1);  Microchemical Journal (4); Journal of Separation Science (3); Journal of Pharmaceutical and Biomedical Analysis (7); Journal of Applied Toxicology (1);  Biomedical Chromatography (8); Comptes Rendus Chimie (1); Analytical Letters (5); Journal of Chemometrics (1); Journal of Inclusion Phenomena and  Macrocyclic Chemistry (1); Separation Science and Technology (1); Journal of Liquid Chromatography and Related Technologies (9); Chemia Analityczna (2);  Arzneimittel-Forschung-Drug Research (1); Revue Roumaine de Chimie (10); LC-GC Europe (1); Nukleonika (1); Acta Endocrinologica (1); Analytical Methods  (1); Bioanalysis (2); Farmacia (1).  Relevant publications (max. 10, citations are given without self-citations):  1. Tache F., David V., Farca A., Medvedovici A. HPLC-DAD determination of Metformin in human plasma using derivatization with p-nitrobenzoyl chloride in a biphasic system, Microchemical Journal, 68(1), 13-19 (2001). Citations: 29 2. Sandra P., Medvedovici A., Zhao Y., David F. Characterization of triglycerides in vegetable oils by silver-ion packed-column supercritical fluid chromatography coupled to mass spectroscopy with atmospheric pressure chemical ionization and coordination ion spray, Journal of Chromatography A, 974(1-2), 231-241 (2002). Citations: 27 3. Tache F., Farca A., Medvedovici A., David V. Validation of a LC-fluorescence method for determination of free captopril in human plasma, using a pre- column derivatization reaction with monobromobimane, Journal of Pharmaceutical and Biomedical Analalysis, 28(3-4), 549-557 (2002). Citations: 19 4. Medvedovici A., Albu F., Georgita C., David V. Non-extractive procedure followed by LC/APCI MS/MS analysis of trimetazidine in plasma samples for assessing bioequivalence of immediate/modified release formulations, Biomedical Chromatography, 19(7), 549-555 (2005). Citations: 15 5. Coman S.M., Florea M., Parvulescu V.I., David V., Medvedovici A., de Vos D., Jacobs P.A., Poncelet G., Grange P. Metal-triflate ionic liquid systems immobilized onto mesoporous MS41 materials as new and efficient catalysts for N-acylation, Journal of Catalysis, 249(2), 359-369 (2007). Citations: 14 6. Albu F., Georgita C., David V., Medvedovici A. Liquid chromatography-electro spray tandem mass spectrometry method for determination of indapamide in serum for single/multiple dose bioequivalence studies of sustained release formulations, Journal of Chromatography B, 816(1-2), 35-40 (2005). Citations: 11 7. Georgita C., Albu F., David V., Medvedovici A. Simultaneous assay of metformin and glibenclamide in human plasma based on extraction-less sample preparation procedure and LC/(APCI)MS, Journal of Chromatography B, 854(1-2), 211-218 (2007). Citations: 8 8. Sandra P., Medvedovici A., David F. Comprehensive pSFC×pSFC-MS for the characterization of triglycerides in vegetable oils, LC GC Europe, 16(12A), 32-34 (2003). Citations: 8 9. Galaon T., Udrescu S., Sora I., David V., Medvedovici A. High-throughput liquid-chromatography method with fluorescence detection for reciprocal determination of furosemide or norfloxacin in human plasma, Biomedical Chromatography, 21(1), 40-47 (2007). Citations: 7 10. Georgita C., Albu F., David V., Medvedovici A. Nonlinear calibrations on the assay of diltiazem and two of its metabolites from plasma samples by means of liquid chromatography and ESI/MS2 detection: application to a bioequivalence study, Biomedical Chromatography, 22(3), 289-297 (2008). Citations: 7 Chapters in Encyclopedias: 1. Tache F., Farca A., Medvedovici A., David V. Captopril, Encyclopedia of Endocrinology and Endocrine Diseases, (L. Martini Ed.), Vol. 1, Elsevier, San Diego, pag. 447-450 (2004). 2. Vasilescu M., Medvedovici  A. Herbicides, Encyclopedia of Analytical Science, 2nd Edition, (A. Townsend Ed.), Academic Press Limited, London, NW1 7DX, U. K., ISBN 0-12-764100-9 (2005). 3. Vasilescu M., Medvedovici A. Pesticides, Encyclopedia of Analytical Science, 2nd Edition, (A. Townsend Ed.), Academic Press Limited, London, NW1 7DX, U. K., ISBN 0-12-764100-9 (2005). 4. Medvedovici A., David V. Diode Array Spectrometry, Encyclopedia of Analytical Science, 2nd Edition, (A. Townsend Ed.), Academic Press Limited, London, NW1 7DX, U. K., ISBN 0-12-764100-9 (2005). 5. Medvedovici A., David V. Pump/solvent delivery system design for HPLC, Encyclopedia of Chromatography (J.Cazes, Ed.), Dekker Publication, New York, on- line version (2006). 6. David V., Medvedovici A. Sample introduction techniques for HPLC, Encyclopedia of Chromatography (J.Cazes, Ed.), Dekker Publication, New York, on-line version (2006). 7. Medvedovici A., David V. Pump/solvent delivery system design for HPLC (new version), Encyclopedia of Chromatography Third Ed. (J.Cazes, Ed.), Dekker Publication, New York, ISBN: 978-1-4200-8459-7, DOI:10.1081/E-ECHR3-120045301, (2010). 8. David V., Medvedovici A. Sample introduction techniques for HPLC (new version), Encyclopedia of Chromatography Third Ed. (J.Cazes, Ed.), Dekker Publication, New York, ISBN: 978-1-4200-8459-7 DOI:10.1081/E-ECHR3-120045307, (2010). No. of libraries (from worldcat.org):  Encyclopedia of Endocrinology and Endocrine Diseases:    93 Encyclopedia of Analytical Science, 2nd Edition:   291 Encyclopedia of Chromatography Third Edition:    34
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